RNA Folding in Ribosome Assembly
Abstract
I want to extend what has been discussed to include the possibility of having proteins direct the folding. As we will see, that is a critical component of what is going on in assembly for the ribosome. Figure 1 is a crystal structure of a piece of RNA with this protein bound to it that was done in our laboratory. I will try to describe the role of a particular protein in guiding some critical steps in RNA folding as the ribosome assembles. The things we are talking about for ribosome assembly are applicable to the formation of all kinds of RNA complexes ...
- Publication:
-
Folding and Self-Assembly of Biological Macromolecules
- Pub Date:
- March 2004
- DOI:
- Bibcode:
- 2004fsab.conf..179W