The Developing Synapse: Construction and Modulation of Synaptic Structures and Circuits
Abstract
Synapse formation and stabilization in the vertebrate central nervous system is a dynamic process, requiring bi-directional communication between pre- and postsynaptic partners. Numerous mechanisms coordinate where and when synapses are made in the developing brain. This review discusses cellular and activity-dependent mechanisms that control the development of synaptic connectivity.
- Publication:
-
Science
- Pub Date:
- October 2002
- DOI:
- 10.1126/science.1075510
- Bibcode:
- 2002Sci...298..770C
- Keywords:
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- NEUROSCIENCE