A memory/adder model constructed from 464 single electromechanical C 60 transistors was recently proposed. Since this is the first large digital electronics architecture that has been designed from hybrid-molecular components only, it has been used to compare the performance of hybrid-molecular devices with current CMOS technology. The scope of this comparison includes issues of size, speed and reliability. Where appropriate, limiting factors resulting from the particular nature of the C 60 transistor are also analyzed in the broader context of other hybrid-molecular approaches and compared with single wall carbon nanotubes (SWCNTs) in an electric field. The features of hybrid-molecular devices, that are to be expected to apply to molecular electronics in general, including recent mono-molecular concepts, are also discussed.