GTPase Signaling: Bridging the GAP between ARF and Rho
Abstract
Membrane traffic and actin cytoskeleton dynamics are intimately linked, and GTPases of the Rho and ARF families may work together to regulate both. Recent studies have identified a family of GTPase activating proteins (GAPs) that contain both ARF-GAP and Rho-GAP domains, providing the first direct link between these two signaling pathways.
- Publication:
-
Current Biology
- Pub Date:
- May 2002
- DOI:
- 10.1016/S0960-9822(02)00860-6
- Bibcode:
- 2002CBio...12.R360S