Fish scale development: Hair today, teeth and scales yesterday?
Abstract
A group of genes in the tumour necrosis factor signalling pathway are mutated in humans and mice with ectodermal dysplasias - a failure of hair and tooth development. A mutation has now been identified in one of these genes, ectodysplasin-A receptor, in the teleost fish Medaka, that results in a failure of scale formation.
- Publication:
-
Current Biology
- Pub Date:
- September 2001
- DOI:
- 10.1016/S0960-9822(01)00438-9
- Bibcode:
- 2001CBio...11.R751S