We report on the properties of the Gaseous Electron Multiplier (GEM) operated at 10-40 Torr isobutane and methane. We found stable operation at gains of a few thousand, fast response and effective photon-feedback reduction. The transmission of single electrons through the GEM apertures was studied. Ion-induced feedback, from a wire chamber following the GEM, was found to limit the total two-stage multiplication at high GEM gains. A stable double-GEM operation with reduced ion-feedback was demonstrated. Some applications are discussed.