The effects of two UVB radiation-absorbing sunscreens on UV radiation-induced carcinogenesis, suppression of the contact hypersensitivity response and histological changes in the hairless mouse
Abstract
The research summarised in this report suggests that the two UVB-absorbers, o-PABA and 2-EHMC, have different modes of protection against UV radiation-induced immunosuppression, carcinogenesis and histological alterations, that appear to be independent of their SPF values, within experimental limits. The UVB-absorber o-PABA appears offer a valuable level of protection against photocarcinogenesis.
- Publication:
-
Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis
- Pub Date:
- January 1998
- DOI:
- Bibcode:
- 1998MRFMM.422..161K
- Keywords:
-
- Sunscreen;
- UVB-absorber;
- Photoimmunosuppression;
- Photocarcinogenesis;
- Hairless mouse