Proton Long-Range Migration along Protein Monolayers and Its Consequences on Membrane Coupling
Abstract
It has been shown with lipid layers and more recently with purple membranes that protons have slow surface-to-bulk transfer. This results in long-range proton lateral conduction along membranes. We report here that such lateral transfer can take place along a pure protein film. It is strongly controlled by the packing. Subtle reorganizations of the protein--protein contact can be biological switches between interfacial and delocalized proton pathways between sources and sinks.
- Publication:
-
Proceedings of the National Academy of Science
- Pub Date:
- December 1996
- DOI:
- 10.1073/pnas.93.25.14521
- Bibcode:
- 1996PNAS...9314521G