The collision of India with Asia is perhaps the most profound tectonic event to have occurred in past 100 Ma. It is responsible for the uplift of the Himalayas and Tibetan Plateau and has been argued to have been responsible for geological, geochemical, and climatological consequences of global extent. Yet the age of initiation of this collision remains poorly constrained. The literature is replete with estimates that range from the Late Cretaceous (> 65 Ma) to latest Eocene (< 40 Ma) with little consensus in between. This paper reviews the available stratigraphic evidence from the Himalayan region, and concludes that only in the western Zanskar-Hazara region is the age well constrained as starting in the Late Ypresian (∼ < 52 Ma). To the east only in the Malla Johar region of the Tethyan Himalayas have potentially syn-collisional sediments been recognized south of the Indus Yarlung Zangbo suture. However, here the correlation of the upper part of the Sangchamalla Flysch is contentious, with correlations ranging from Late Cretaceous to Middle Eocene (Lutetian). In the most eastern sections of Tertiary rocks thus far recognized within the Tethyan Himalayas north and east of Everest (Mount Qomolangma) normal, shallow shelf-type carbonates extend into the Lutetian, without evidence of a change in sedimentation to the top of the section, so the start of collision must be still younger. Along-strike of the Indus Yarlung Zangbo suture thick submarine delta-fan complexes derived from erosion of the Himalayan-Tibet system provide independent estimates that agree with a diachronous collision initiating in the late Ypresian in the west and progressing into and perhaps through the Lutetian in the east. The stratigraphic and magmatic history along the north side of the suture are compatible with such a diachronous history. This diachroneity has important implications for estimates of the accommodation of strain within this orogenic system.