By using telescience techniques, we developed and tested a system for remotely conducting intracellular recordings, an indispensable method for biomedical studies. As a representative experiment we chose to study on the adenosine-induced responses of Xenopus oocyte. Experimental materials were placed in a room simulating an orbital laboratory. The experiment was controlled and monitored by a principal investigator (PI) from another room simulating a ground control room. The two rooms were connected by a telecommunication simulator that could impose the communication delay and limit the data transfer rate. The PI inserted one or two microelectrodes into an oocyte using remote control on the micro-manipulators and on the platform of microscope with stereoscopic pictures observed through a head mounted display. By inserting one electrode, we could successfully study the adenosine responses at various concentrations. Then, we tried to perform the "voltage clamp" recordings by inserting two electrodes into one oocyte. Though insertion of two electrodes was troublesome, we finally succeeded the voltage clamp recordings. Result indicate the usefulness of the telescience for conducting intracellular recordings in space.