The dental amalgam mercury controversy — inorganic mercury and the CNS; genetic linkage of mercury and antibiotic resistances in intestinal bacteria
Abstract
Mercury (Hg) vapor exposure from dental amalgam has been demonstrated to exceed the sum of all other exposure sources. Therefore the effects of inorganic Hg exposure upon cell function in the brain and in the intestinal bacteria have recently been examined. In rats we demonstrate that ADP-ribosylation of tubulin and actin brain proteins is markedly inhibited, and that ionic Hg can thus alter a neurochemical reaction involved with maintaining neuron membrane structure. In monkeys we show that Hg, specifically from amalgam, will enrich the intestinal flora with Hgresistant bacterial species which in turn also become resitant to antibiotics.
- Publication:
-
Toxicology
- Pub Date:
- January 1995
- DOI:
- 10.1016/0300-483X(94)02964-V
- Bibcode:
- 1995Toxgy..97...19L
- Keywords:
-
- Dental amalgam;
- Inorganic mercury;
- Central nervous system;
- Antibiotic resistances