Principles of CDK regulation
Abstract
As key regulators of the cell cycle, the cyclin-dependent kinases must be tightly regulated by extra- and intracellular signals. The activity of cyclin-dependent kinases is controlled by four highly conserved biochemical mechanisms, forming a web of regulatory pathways unmatched in its elegance and intricacy.
- Publication:
-
Nature
- Pub Date:
- March 1995
- DOI:
- 10.1038/374131a0
- Bibcode:
- 1995Natur.374..131M