The maximal explosive power of the lower limbs of one astronaut has been measured before launch, and 2, 6 and 11 days after re-entry from 31 days on the IIR. Station (EUROMIR '94). The subject, sitting on the carriage-seat of a Multipurpose Ergometer-Dynamometer (MED) constructed ad hoc in our laboratory, pushed maximally with both feet on two force platforms (knees angle 110 °). The carriage was free to move backwards on two rails inclined 20 ° upwards. The force (F) of the lower limbs and the speed of the carriage (v) were recorded and the instantaneous mechanical power (ẇ) was calculated as ẇ = F ∗ v. The average value mechanical power (ẇ max) throughout the explosive effort was then obtained. The overall duration of the push was on the average about 0.3 s. It was observed that, at day R + 2, mean force, maximal velocity, maximal power (mean and peak), maximal acceleration and overall mechanical work, were all reduced between 60 and 80% of pre-flight values. However, the recovery was remarkably fast, since all these parameters attained about 90% of pre-flight values by day R + 11.