It is pointed out that string-loop modifications of the low-energy matter couplings of the dilation may provide a mechanism for fixing the vacuum expectation value of a massless dilation in a way which is naturally compatible with existing experimental data. Under a certain assumption of universality of the dilation coupling functions, the cosmological evolution of the graviton-dilaton-matter system is shown to drive the dilaton towards values where it decouples from matter (``Least Coupling Principle''). Quantitative estimates are given of the residual strength, at the present cosmological epoch, of the coupling to matter of the dilaton. The existence of a weakly coupled massless dilaton entails a large spectrum of small, but non-zero, observable deviations from general relativity. In particular, our results provide a new motivation for trying to improve by several orders of magnitude the various experimental tests of Einstein's Equivalence Principle (universality of free fall, constancy of the constants, etc.).