Use of the Zetatron D-T neutron generator for the simultaneous measurement of carbon, oxygen, and hydrogen in vivo in humans
Abstract
A small sealed D-T neutron generator is used for the pulsed (4-8 kHz) production of fast neutrons. Carbon and oxygen are detected in vivo by counting the 4.44 and 6.13 MeV gamma rays resulting from the inelastic scattering of the fast neutrons. Hydrogen is detected by thermal neutron capture. BGO detectors (127 mm diameter × 76 mm thick) were found more tolerant to neutron exposure and improved the signal to background ratio for the carbon detection by a factor of 6, compared to 152 × 152 mm NaI(Tl). The elemental analysis of the body is used to study the changes of body composition with aging. We investigate the causes of depletion of lean body mass and the development of ways of maintaining functional capacity and quality of life of the elderly.
- Publication:
-
Nuclear Instruments and Methods in Physics Research B
- Pub Date:
- June 1993
- DOI:
- 10.1016/0168-583X(93)95412-X
- Bibcode:
- 1993NIMPB..79..555K