High efficiency photo-induced dissociation of precursor ions in a tandem time-of-flight mass spectrometer
Abstract
High efficiency photo-induced dissociation (PID) has been demonstrated in a tandem time-of-flight mass spectrometer. This intrument focuses isomass ion packets to temporal and spatial dimensions similar to those of the focused laser pulses from a high power excimer laser. This high density overlap of photons and ions yields highly efficient fragmentation and also provides high resolution selection of specific precursor ion mass-to-charge ratio values. Using 193 nm photon excitation of the molecular ion of bromobenzene ( m/z = 156), fragmentation, collection, and PID efficiencies of 79%, 132%, and 104%, respectively, were obtained. Characteristic fragmentations of toluene, nitrobenzene, acetophenone, triethylamine, N,N-diethylformamide, N-methylacetamide, and cyclohexene have also been demonstrated.
- Publication:
-
Journal of The American Society for Mass Spectrometry
- Pub Date:
- January 1993
- DOI:
- 10.1016/1044-0305(93)80055-4
- Bibcode:
- 1993JASMS...4..751S