Involvement of p34cdc2 in establishing the dependency of S phase on mitosis
Abstract
Mutants of cdc2+ can disrupt the dependency of S phase on completion of the previous mitosis. By changing the state of p34cdc2 it is possible to reprogramme a cell from entering mitosis to undergoing S phase. This leads to the proposal that the cell cycle can be considered a p34cdc2 cycle, and has implications for the evolution of life cycles.
- Publication:
-
Nature
- Pub Date:
- January 1991
- DOI:
- 10.1038/349388a0
- Bibcode:
- 1991Natur.349..388B