The total galaxy set of the Jagiellonian catalogue (6°×6°,N=15650 galaxies) has undergone two-dimensional clusterization procedure. The position angle of the major axis and the ratio of axes of the effective ellipse of inertion are calculated for every cluster. The histograms ‘position angle — number of galaxies’ are investigated for the different samples of clusters. The histograms at the certain radii of clusterization (R=2' 3') and galaxy population levels (6≤N min≤15) demonstrate the pronounced and statistically significant anisotropy with the smooth trend along the position angleF and preferable orientation in the range ofF=105° 120°. When we take into consideration the systematical catalogue errors, the problem of reality of this effect has been analysed. The question about possible space scale of anisotropy is discussed. Its lower limit is evaluated by magnitude 500 Mps. One cannot explain the result obtained by influence of systematical errors of catalogue, as in that case they would have to be enormous.