Dictyostelium discoideum: A Model System for Cell-Cell Interactions in Development
Abstract
The cellular slime mold Dictyostelium discoideum undergoes a transition from single-celled amoebae to a multicellular organism as a natural part of its life cycle. A method of cell-cell signaling that controls chemotaxis, morphogenesis, and gene expression has developed in this organism, and a detailed understanding of this signaling system provides clues to mechanisms of intercellular communication in the development of metazoans.
- Publication:
-
Science
- Pub Date:
- September 1989
- DOI:
- 10.1126/science.2672337
- Bibcode:
- 1989Sci...245.1054D