The bicoid protein is a positive regulator of hunchback transcription in the early Drosophila embryo
Abstract
A gradient in concentration of the protein product of the bicoid gene is a determinant of the anterior-posterior axis of Drosophila embryos. By binding upstream of the segmentation gene hunchback the bicoid protein controls its transcription, thereby translating maternal pattern-generating information into differential activation of zygotic gene expression.
- Publication:
-
Nature
- Pub Date:
- January 1989
- DOI:
- 10.1038/337138a0
- Bibcode:
- 1989Natur.337..138D