Mammalian valyl-tRNA synthetase forms a complex with the first elongation factor
Abstract
The high-molecular-mass form of valyl-tRNA synthetase is associated with the first elongation factor activity. It includes two polypeptides of about 50 kDa and two others of 40 and 30 kDa, identified as α, β, γ and δ subunits of eEF-1H. The complex of valyl-tRNA synthetase with eEF-1H is suggested to be a novel form of the first elongation factor.
- Publication:
-
FEBS Letters
- Pub Date:
- January 1988
- DOI:
- 10.1016/0014-5793(88)80492-7
- Bibcode:
- 1988FEBSL.238..262M
- Keywords:
-
- valyl-tRNA synthetase;
- First elongation factor;
- High-molecular-mass complex