Three-dimensional structure of a complex of antibody with influenza virus neuraminidase
Abstract
The structure of a complex between influenza virus neuraminidase and an antibody displays features inconsistent with the inflexible 'lock and key' model of antigen-antibody binding. The structure of the antigen changes on binding, and that of the antibody may also change; the interaction therefore has some of the character of a handshake.
- Publication:
-
Nature
- Pub Date:
- March 1987
- DOI:
- 10.1038/326358a0
- Bibcode:
- 1987Natur.326..358C