Consider measurements that provide information about the position of a nonrelativistic, one-dimensional, quantum-mechanical system. An outstanding question in quantum mechanics asks how to analyze measurements distributed in time-i.e., measurements that provide information about the position at more than one time. I develop a formulation in terms of a path integral and show that it applies to a large class of measurements distributed in time. For measurements in this class, the path-integral formulation provides the joint statistics of a sequence of measurements. Specialized to the case of instantaneous position measurements, the path-integral formulation breaks down into the conventional machinery of nonrelativistic quantum mechanics: a system quantum state evolving in time according to two rules-between measurements, unitary evolution, and at each measurement, ``collapse of the wave function'' (``reduction of the state vector''). For measurements distributed in time, the path-integral formulation has no similar decomposition; the notion of a system quantum state evolving in time has no place.