Silicone Rubber Substrata: A New Wrinkle in the Study of Cell Locomotion
Abstract
When tissue cells are cultured on very thin sheets of cross-linked silicone fluid, the traction forces the cells exert are made visible as elastic distortion and wrinkling of this substratum. Around explants this pattern of wrinkling closely resembles the ``center effects'' long observed in plasma clots and traditionally attributed to dehydration shrinkage.
- Publication:
-
Science
- Pub Date:
- April 1980
- DOI:
- 10.1126/science.6987736
- Bibcode:
- 1980Sci...208..177H