Circulating immune complexes in infants fed on cow's milk
Abstract
CIRCULATING antigen-antibody (AgAb) complexes are capable of damaging various tissues, for example, renal glomeruli, vessels and joints1. In addition, immune complexes (IC) can interfere with cellular immunity and, to some extent, decrease the immune response2-4. We report here that all infants fed on cow's milk have circulating complexes containing bovine proteins as antigens and IgG antibodies of maternal origin. These data raise questions as to the possible involvement of such complexes in various disorders, the intestinal resorption of macromolecules, and the development of antibodies against food antigens.
- Publication:
-
Nature
- Pub Date:
- April 1978
- DOI:
- 10.1038/272632a0
- Bibcode:
- 1978Natur.272..632D