Stability of the Individual Globin Genes During Erythroid Differentiation
Abstract
The genes for sheep β A, β C, and γ globin were all present in DNA from erythroid cells which synthesized only β C globin. Similarly, selective excision of non-expressed genes was shown not to occur during human erythroid differentiation. In contrast, evolutionary deletion of the β C gene accounts for the inability of many sheep to make this globin.
- Publication:
-
Science
- Pub Date:
- June 1977
- DOI:
- 10.1126/science.860136
- Bibcode:
- 1977Sci...196.1213B