Rolling hairpin model for replication of parvovirus and linear chromosomal DNA
Abstract
A novel, quasicircular scheme is proposed for the replication of parvovirus DNA. Daughter strands are initiated after the copying and rearrangement of a terminal palindromic sequence, a process termed `hairpin transfer'. Such a process may be involved in the replication of other viruses and host cell DNA.
- Publication:
-
Nature
- Pub Date:
- September 1976
- DOI:
- 10.1038/263106a0
- Bibcode:
- 1976Natur.263..106T