Neutron Diffraction Studies on the Location of Water in Lecithin Bilayer Model Membranes
Abstract
Lamellar neutron diffraction from oriented multilayers of hydrated dipalmitoyl lecithin was phased by isomorphous H2O-D2O exchange and swelling techniques. Bound water sites were located in the polar head group region of the bilayer profile. A 6-Å resolution structure based on the neutron scattering density profile is proposed for the bilayer. It is consistent with the electron density profile from x-ray diffraction.
- Publication:
-
Proceedings of the National Academy of Science
- Pub Date:
- January 1975
- DOI:
- 10.1073/pnas.72.1.376
- Bibcode:
- 1975PNAS...72..376Z