Activation of Transcription of hut DNA by Glutamine Synthetase
Abstract
The correct transcription of the hut (histidine utilization) operon DNA of Salmonella typhimurium requires activation either by 3‧:5‧-cyclic adenosine monophosphate and catabolite-activating protein or by nonadenylylated glutamine synthetase (EC 6.3.1.2.). Thus, glutamine synthetase plays a regulatory role distinct from its enzymatic function.
- Publication:
-
Proceedings of the National Academy of Science
- Pub Date:
- January 1974
- DOI:
- 10.1073/pnas.71.1.225
- Bibcode:
- 1974PNAS...71..225T