Dynamics of Carbon Monoxide Binding by Heme Proteins
Abstract
Rebinding of carbon monoxide to myoglobin and to cytochrome P-450 after removal by a light flash occurs down to 50^circK for myoglobin and 25^circK for cytochrome P-450 in glycerol-water solution. Above 240^circK the reaction is second order; between 240^circ and 200^circK the rebinding becomes exponential and independent of the carbon monoxide concentration. Below 150^circK the reaction follows a power law and is approximately 103 times faster for cytochrome P-450 than for myoglobin.
- Publication:
-
Science
- Pub Date:
- August 1973
- DOI:
- 10.1126/science.181.4099.541
- Bibcode:
- 1973Sci...181..541A