Genetics of Human-Mouse Somatic Cell Hybrids: Linkage of Human Genes for Lactate Dehydrogenase-A and Esterase-A4
Abstract
By use of human-mouse somatic cell hybrids, an autosomal gene linkage has been determined for the human loci controlling the phenotypes of lactate dehydrogenase-A (EC 1.1.1.27) and esterase-A4 (EC 3.1.1.2). These structural loci were not linked to the lactate dehydrogenase-B, peptidase-B linkage, the X chromosome, the E17 chromosome, or to nine other enzyme phenotypes examined.
- Publication:
-
Proceedings of the National Academy of Science
- Pub Date:
- February 1972
- DOI:
- 10.1073/pnas.69.2.348
- Bibcode:
- 1972PNAS...69..348S