On the Identity of DOPA Decarboxylase and 5-Hydroxytryptophan Decarboxylase
Abstract
Simultaneous immunological titration of DOPA and 5-hydroxytryptophan decarboxylase activities, from a number of tissues of various species, showed that the two activities were not distinguishable with a monospecific antiserum to hog kidney decarboxylase. Together with previous findings, these data firmly establish the concept that in mammalian tissues the two enzyme activities are associated with a single protein, namely aromatic L-amino acid decarboxylase.
- Publication:
-
Proceedings of the National Academy of Science
- Pub Date:
- February 1972
- DOI:
- 10.1073/pnas.69.2.343
- Bibcode:
- 1972PNAS...69..343C