Adenosine Triphosphatase Associated with Adenosine Triphosphate-Dependent Deoxyribonuclease
Abstract
An ATPase activity that is completely dependent on DNA is associated with the ATP-dependent DNase (recB-recC enzyme) purified from Escherichia coli. There is a strong correlation between the ATPase and the DNase activities under various assay conditions. With E. coli DNA as substrate, 8-9 molecules of ATP are hydrolyzed to ADP and inorganic phosphate for every phosphodiester bond hydrolyzed by the DNase. The possible functional relationship of the ATPase and DNase activities is discussed.
- Publication:
-
Proceedings of the National Academy of Science
- Pub Date:
- January 1972
- DOI:
- 10.1073/pnas.69.1.15
- Bibcode:
- 1972PNAS...69...15N