Prediction of RNA Secondary Structure
Abstract
Calculations of the free energy required to close single-strand loops by formation of a base pair in double-helical nucleic acids are reported. These results can be used to estimate the free energy of particular secondary structures for a given RNA molecule under conditions of high-salt concentration.
- Publication:
-
Proceedings of the National Academy of Science
- Pub Date:
- November 1971
- DOI:
- 10.1073/pnas.68.11.2682
- Bibcode:
- 1971PNAS...68.2682D