Evidence for Position-Effect Suppression of the Ribosomal RNA Cistrons in Drosophila melanogaster
Abstract
Unambiguous evidence is presented that two X-chromosome inversions produce lethality in X/O males because of position-effect suppression of genes in the basal heterochromatin. The data support the hypothesis that the ribosomal RNA cistrons are the genes suppressed. There is evidence for a region in the X basal heterochromatin that may act as a regulator of rDNA activity.
- Publication:
-
Proceedings of the National Academy of Science
- Pub Date:
- October 1971
- DOI:
- 10.1073/pnas.68.10.2472
- Bibcode:
- 1971PNAS...68.2472B