Indole(ethyl)amine N-Methyltransferase in the Brain
Abstract
An enzyme which N-methylates various indole(ethyl)amine substrates was isolated from brain, separated from the pituitary and the pineal glands. It appeared localized in the supernatant and synaptosomal areas after discontinuous sucrose-gradient ultracentrifugation. This is the first demonstration of the enzyme in brain.
- Publication:
-
Science
- Pub Date:
- August 1969
- DOI:
- 10.1126/science.165.3892.492
- Bibcode:
- 1969Sci...165..492M