Chick Cartilage Collagen: A New Type of α 1 Chain not Present in Bone or Skin of the Species
Abstract
Isolation and chromatography of collagen from chick cartilage revealed an excess of α1 relative to α2-chains. Characterization of the cyanogen bromide peptides from the α1 fraction indicated the presence of two homologous forms of α1. The results suggest that cartilage contains two collagens, one identical to the collagen of skin and bone, the other clearly different requiring the expression of an additional structural gene and possibly containing only α1-chains.
- Publication:
-
Proceedings of the National Academy of Science
- Pub Date:
- December 1969
- DOI:
- 10.1073/pnas.64.4.1264
- Bibcode:
- 1969PNAS...64.1264M