Toxicity of Pyrrolizidine Alkaloids
Abstract
A new class of metabolite, with a pyrrole-like structure, has been demonstrated in the tissues of animals poisoned by pyrrolizidine alkaloids. There is some correlation between the degree of hepato-toxicity and the amount of ``pyrrole'' found in the liver. Evidence has been found of the types of reactions such metabolites might undergo with tissue constituents.
- Publication:
-
Nature
- Pub Date:
- February 1968
- DOI:
- 10.1038/217723a0
- Bibcode:
- 1968Natur.217..723M