Prevention of Fatty Liver by Administration of Adenosine Triphosphate
Abstract
IT has recently been shown that the fatty liver produced in rats by ethionine administration is associated with a decrease in hepatic adenosine triphosphate (ATP) levels and that injections of ATP are able to prevent both the fatty liver and the drop in ATP1,2. We have observed that a variety of agents which produce a fatty liver lead to decreased ATP concentrations in the liver and that the protective effects of ATP administration are not limited to ethionine toxicity.
- Publication:
-
Nature
- Pub Date:
- December 1964
- DOI:
- 10.1038/2041196a0
- Bibcode:
- 1964Natur.204.1196H