Effect of Chemical Protective Agents (Cysteamine and β-Aminoethylisothiuronium (AET) Cl HCl) and Homologous Testes-DNA on the Death-rate of the Progeny of a First Generation originating from Male Rats irradiated in the Infantile Period
Abstract
IT is well known that irradiation causes death of the progeny of adult irradiated animals. For example, Osipovskii1 found that the death-rate of the progeny of males irradiated with an X-ray dose of 360 r. reaches 53 per cent. Hertwig2 found that the percentage of dead progeny in the period from their birth to the seventy-fifth day of age is considerably higher than later. Strandskow3 also found an increased death-rate in the progeny of irradiated male guinea pigs for the period up to 30 days of age. Henson3 also observed the death-rate of the progeny of male rats irradiated with an X-ray dose of 100-1,000 r. during their lactation period. It has been found that 46 per cent of the progeny live until the end of the lactation period. Observing the changes on the progeny of male mice irradiated with 25 MeV through five generations, Proshina4 found the highest death-rate in the first generation and in the first month of life.
- Publication:
-
Nature
- Pub Date:
- September 1964
- DOI:
- 10.1038/2031393a0
- Bibcode:
- 1964Natur.203.1393S