X-rays Affect the Incorporation of 5-Iododeoxyuridine into Deoxyribonucleic Acid
Abstract
When labeled with iodine-131, 5-iododeoxyuridine, an analogue of thymidine, is useful in estimating the effect of x-radiation on deoxyribonucleic acid metabolism. Although this compound is readily incorporated into deoxyribonucleic acid in the absence of ionizing radiation, we find that whole-body exposure to as little as 10 r will significantly inhibit its incorporation.
- Publication:
-
Science
- Pub Date:
- April 1961
- DOI:
- Bibcode:
- 1961Sci...133.1074G