The Aldermaston Tandem and 6 MV electrostatic generators are being used for the study of nuclear reactions produced by protons, deuterons, tritons and He 3 ions in the bombarding energy range up to 12 MeV. The angular distributions of the emitted charged particles are measured with large magnetic analysers, which include a multi-channel broad range spectrograph with twenty four gaps. The results show that at the higher bombarding energies, the reactions proceed predominately by a direct mechanism. Oxygen ions accelerated in the Tandem generator to energies in the range 10 MeV to 40 MeV have been used for Coulomb excitation of energy levels in both rotational and vibrational nuclei and for the measurement of nuclear lifetimes by Doppler shift methods. As a consequence of the large momentum transfer from the incident ions to the target and residual nuclei, Doppler shifts of the emitted γ-rays may be up to an order of magnitude greater than in light particle reactions, and the technique is useful for measuring lifetimes in the range 10 -14 to 10 -11 second. Methods of producing ion beams of higher energy by combinations of electrostatic generators are also discussed briefly.