Use of an Organic Carbon Dioxide Buffer in vivo
Abstract
The compound 2-amino-2(hydroxymethyl)1,3-propane diol was administered intravenously to apneically oxygenated dogs over a 1-hour period. Arterial blood pH remained normal, and an estimated 18 to 28 percent of the CO2 produced during apnea was recovered in the urine.
- Publication:
-
Science
- Pub Date:
- March 1959
- DOI:
- 10.1126/science.129.3351.782
- Bibcode:
- 1959Sci...129..782N