Oxidative Degradation of Testosterone by Adaptive Enzymes
Abstract
THE study of steroid synthesis by micro-organisms and certain oxidations and reductions of reactive groups at positions 3 and 17 of the steroid skeleton have been previously reported1. Turfitt2 has studied more extensive degradations of cholesterol by bacteria and has isolated products in which the side-chain has been removed and ring A opened. We should like to report the application of adaptive bacterial enzymes to the study of the oxidative degradation of steroid hormones.
- Publication:
-
Nature
- Pub Date:
- October 1952
- DOI:
- 10.1038/170620a0
- Bibcode:
- 1952Natur.170..620T