Frequency of Microcythæmia in some Italian Districts
Abstract
IT has been demonstrated1 that `microcythæmia' or `thalasshæmia' depends on a single gene pair with semi-dominance. The heterozygotes Mm are microcythæmics, that is, entirely viable individuals, either normal, or suffering from a mild form of anhæmia. The homozygotes MM, on the contrary, are affected by Cooley's disease and die early in childhood. The two forms are also called by American authors `thalasshæmia minor' (Mm), and `thalasshæmia major' (MM).
- Publication:
-
Nature
- Pub Date:
- April 1950
- DOI:
- 10.1038/165682a0
- Bibcode:
- 1950Natur.165..682S