Curare
Abstract
IN 1931 Hartridge and West1 noted a rigidity-removing (`lissive') action of curare in experimental parathyroid tetany in dogs. The application of the drug to diseases involving muscular rigidity in man was undertaken by West in a wide series of cases2. As it was observed quite early in the investigations that the `lissive' action was apparently only present in certain samples of curare and might be due to some constituent other than the `curarines' to which the classical action of curare is due, a broad chemical survey of the much neglected field of the curares was undertaken by the writer in close co-operation on the pharmacological side with Dr. Ranyard West.
- Publication:
-
Nature
- Pub Date:
- March 1935
- DOI:
- 10.1038/135469b0
- Bibcode:
- 1935Natur.135..469K