Solvent-Controlled Cascade Reaction of Ugi/Pd-Catalyzed Intramolecular Divergent C-H Functionalization for Regioselective Synthesis of Cyclopropanated N-Heterocycles
Abstract
A novel cascade reaction of Ugi/Pd-catalyzed intramolecular divergent C-H functionalization, which is controlled by solvent effect to achieve the regioselective synthesis of spiro- and fused-cyclopropanated indolines from the Ugi adduct of N-acylated 2-bromoarylamides.
- Publication:
-
Materials Science and Engineering Conference Series
- Pub Date:
- October 2019
- DOI:
- 10.1088/1757-899X/612/2/022108
- Bibcode:
- 2019MS&E..612b2108S