Some Properties of Angiotensin Converting Enzyme in the Lung in vivo
Abstract
THE lung has many important metabolic functions1,2 which include the selective activation or inactivation of endogenous peptides. Bradykinin is inactivated on transit through the pulmonary circulation3,4, probably by at least two endopeptidases5, but other peptides such as angiotensin II (refs. 6-10), polistes kinin11 and eledoisin3,4 pass through without loss.
- Publication:
-
Nature
- Pub Date:
- March 1970
- DOI:
- 10.1038/2251142b0
- Bibcode:
- 1970Natur.225.1142N