Virus Interference. I. The Interferon
Abstract
During a study of the interference produced by heat-inactivated influenza virus with the growth of live virus in fragments of chick chorio-allantoic membrane it was found that following incubation of heated virus with membrane a new factor was released. This factor, recognized by its ability to induce interference in fresh pieces of chorio-allantoic membrane, was called interferon. Following a lag phase interferon was first detected in the membranes after 3 h incubation and thereafter it was released into the surrounding fluid.
- Publication:
-
Proceedings of the Royal Society of London Series B
- Pub Date:
- September 1957
- DOI:
- 10.1098/rspb.1957.0048
- Bibcode:
- 1957RSPSB.147..258I